ARA290 10mg

ARA-290 (also known as pyroglutamate helix B surface peptide) is an 11-amino-acid peptide derived from erythropoietin (EPO). Designed specifically to promote tissue repair and reduce inflammation, it is primarily studied for its ability to relieve neuropathic pain and heal nerve fibers without causing the red blood cell production associated with EPO.How ARA-290 WorksUnlike traditional EPO, ARA-290 does not bind to hematopoietic receptors, meaning it avoids cardiovascular risks like increased blood viscosity. Instead, it interacts exclusively with the Innate Repair Receptor (IRR).When the IRR is activated by ARA-290, it triggers several physiological responses:Anti-inflammation: It downregulates pro-inflammatory cytokines and suppresses the activation of microglia (immune cells in the nervous system associated with neuroinflammation).Pain Reduction: Studies have shown it specifically acts as an antagonist for the TRPV1 channel, helping to alleviate neuropathic and pathophysiological pain.Tissue Regeneration: It actively promotes the repair and regrowth of small nerve fibers, which has been observed in both animal models and human trials.